Rational design is a research approach that involves using scientific principles and computational methods to design new molecules, materials, or compounds with specific properties or functions. This approach relies on a deep understanding of the underlying mechanisms and relationships in a system, allowing researchers to predict and manipulate the structure and behavior of the designed entity. Rational design is commonly used in drug discovery, materials science, and biotechnology to create more efficient and effective solutions for various applications. It is a powerful tool for accelerating the development of new products and technologies by streamlining the design process and reducing the need for trial-and-error experimentation.